St. John's Wort

Brain & Cognitive Health Mood & Mental Wellbeing

St. John's wort is a flowering plant in the family Hypericaceae. The flowers are used to make herbal preparations. It has been used in traditional medicine for centuries to treat various health issues.

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Quick Facts

Best for
Mild depression, Mood swings, Anxiety
Common form
Tea, tincture, capsule, food, or topical preparation depending on the remedy.
Caution level
High - many medication interactions
Related searches
Mild depression, Mood swings, Anxiety, Seasonal affective disorder, Nervous tension
Author Eden Editorial Team
Reviewed by Editorial safety review pending clinician review
Last updated 2026-04-29

How this remedy page was created

Created from Eden's remedy database, traditional-use context, and public health references. Educational only; not a diagnosis or treatment plan.

Image disclosure: remedy images are AI-assisted only when marked reviewed for botanical accuracy.

Benefits

May help with mild to moderate depression

Can improve mood and reduce anxiety

Has anti-inflammatory properties

Traditionally used for wound healing

May help with seasonal affective disorder (SAD)

The Science & Wisdom Behind St. John's Wort

Scientific Evidence

St. John's wort contains hypericin and hyperforin, which may increase the levels of chemical messengers in the brain like serotonin, dopamine, and noradrenaline, similar to how some prescription antidepressants work.

Traditional Use

The plant was named after St. John the Baptist, as it traditionally blooms around his feast day. In medieval times, it was believed to have magical properties that could ward off evil spirits.

Anecdotal Reports

Many people who experience mild depression report improved mood, better sleep, and reduced anxiety when taking St. John's wort regularly, though it may take 4-6 weeks to see full effects.

How to Use St. John's Wort

General Usage

St. John's wort is typically taken as a standardized extract in capsule or tablet form, though it can also be consumed as tea or tincture.

Common Uses For:

Mild depression Mood swings Anxiety Seasonal affective disorder Nervous tension

Recipe

St. John's Wort Tea: Steep 1-2 teaspoons of dried St. John's wort (flowers and leaves) in hot water for 5-10 minutes. Drink up to 3 cups daily.

Safety & Cautions

Natural does not always mean risk-free. Use this section to decide when a remedy deserves extra care or a clinician conversation.

Key cautions

  • ! St. John's Wort has many clinically important medication interactions.

Avoid or get medical guidance first

  • ! Avoid with antidepressants, birth control pills, transplant medicines, HIV medicines, blood thinners, and many other prescriptions unless clinician-approved.

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